Mouthwatering Cattle Drive Layers

Category: Where Culinary Traditions Collide

Get ready for a tasty comfort meal. Tender beef with onions and peppers gets tossed with taco spice, then layered over biscuit dough that's baked first for a sturdy bottom. A tangy, creamy blend of mayo, green chiles, cheddar, and sour cream melts in between. Salsa adds extra zip, and the bubbly melted cheese on top seals the deal. It comes out of the oven piping hot and golden, with punchy flavor and plenty to go around for everyone.

Monica
By Monica Monica
Updated on Sat, 19 Jul 2025 15:09:58 GMT
Slice of cheesy layered casserole with herbs on top. Pin
Slice of cheesy layered casserole with herbs on top. | flavorsfuse.com

This beefy bake packs a punch with rustic Tex-Mex flavors, piling a hearty biscuit crust, zesty meat, and gooey cheese into every bite. Folks can’t help but go back for seconds thanks to its crowd-pleasing layers. When I’m looking for big flavor and leftovers you’ll want for lunch, this is always my pick.

First time I whipped this up, not a crumb was left! My crew asked if I could double it next time. Now it’s our must-have for Saturday get-togethers.

Delicious Ingredients

  • Cheddar cheese fiesta blend: melts so nice and has big sharp flavor grate it fresh for the best stretch
  • Sour cream: brings creaminess and a little zip full fat works best for a smooth finish
  • Red bell pepper: makes it pop with color and a bit of sweetness pick a glossy firm one
  • Lean ground beef: anchors the dish with bold taste and lots of protein aim for beef with barely any fat showing for best results
  • Taco seasoning: amps up each layer with big south of the border flavor choose one with a punchy spice blend
  • Salsa: adds sparkle and brings the Tex Mex vibe together use a style you love, jarred or fresh
  • Biscuit mix: gives you that fluffy hearty bottom layer stick to reliable brands for no-fail texture
  • Cooking spray: makes it a breeze to get out of the pan
  • Mayonnaise: makes the creamy layer pleasantly rich use a good mayo for clean flavor
  • Yellow onion: sets up the whole dish with depth and savory notes dry skin tells you it’s fresh
  • Diced green chiles: toss in mild heat without burning your mouth drain well so nothing gets runny
  • Garlic powder: bumps up the savory kick
  • Water: helps bring the biscuit dough together keep it cold so your hands don’t stick

Simple Steps

Bake It:
Pop it back in the oven uncovered for about thirty minutes, until you see the cheese bubbling hot and beautifully golden. Let it chill for several minutes before you cut so your slices stay tidy.
Finish with Salsa and Cheese:
Spread salsa over the creamy layer in spoonfuls, letting the juices soak through, and finish off with your leftover cheese scattered all over the top for an irresistible crust.
Get the Creamy Layer Ready:
Grab a mixing bowl and stir together sour cream, mayo, drained chiles, garlic powder, and almost all the cheese until it’s totally smooth. Carefully smooth this thick layer over your meat without tearing the bottom.
Stack the Layers:
Spoon the seasoned meat and veggies onto the baked biscuit base, smoothing to the edges so each bite is covered and nothing is missed.
Soften the Veggies:
Once the meat is cooked, toss in chopped onions and red pepper, cooking till they’re soft and smell sweet, about four minutes. Stir in taco seasoning and take off heat.
Work the Biscuit Dough:
Blend biscuit mix with cold water using your hands until you get a smooth dough. Spray your baking dish so nothing sticks, then press dough into the bottom (and a little up the sides). Put in oven just until edges are golden and crust looks set—it’ll hold up the filling perfectly.
Brown the Meat:
On medium-high, cook the ground beef in a big skillet, breaking it up and letting it brown. When it’s no longer pink and has great texture, tip out any extra grease so each slice isn’t oily.
Start the Oven:
Get things rolling by heating your oven up to three fifty so it’s ready for baking magic later.
A yummy wedge of cheesy baked casserole. Pin
A yummy wedge of cheesy baked casserole. | flavorsfuse.com

Honestly, the best part for me is scooping up a chunk of that cheesy top, catching all the creamy layers and beef. Makes me think of movie night with the gang and everyone digging in at the table together.

Storing Leftovers

Once it’s cooled, move leftovers into a sealed container and stash in your fridge—they’ll last about four days. You can freeze slices, too, wrapped up or in a container. Reheat gently in the microwave or oven when you want a quick meal.

Swap Options

Want to shake things up? Try Monterey Jack or pepper jack for a switch on flavor or heat. Ground turkey keeps it a little lighter. Swap in light sour cream for fewer calories. Gluten-free biscuit mix (and double-check your taco seasoning) makes it safe if you can’t have gluten.

How to Serve

I love piling this onto a plate with a zingy green salad tossed with lime, or next to beans and rice for extra filling power. Slices of avocado or a dollop of sour cream make it over the top. Grab some chips to get every last bite.

A cheesy, gooey slice of layered casserole fresh from the oven. Pin
A cheesy, gooey slice of layered casserole fresh from the oven. | flavorsfuse.com

Where It Comes From

This layered comfort dish borrows from cowboy campfire stews and Southwestern casseroles. The biscuit base nods to classic Southern food, while spicy beef and peppers reflect longtime Tex-Mex family cooking.

FAQs About the Recipe

→ Which ground beef should I use?

Lean beef's your best bet. Try an 80/20 or 85/15 mix if you want beef that's moist without being greasy.

→ Can I swap out the cheese?

Totally, go for cheddar or shredded fiesta blend, or grab some pepper jack, Monterey Jack, or Mexican mix if that's what you've got.

→ Can I assemble it ahead of time?

You sure can! Stack your layers a day before, cover them, and stash in the fridge. Toss it in the oven when you're ready to eat.

→ Will this freeze well after it's baked?

Absolutely. Let it cool off, wrap it tight, and freeze. Defrost in the fridge before warming up so it heats evenly and stays tasty.

→ What should I serve on the side?

Fresh green salad, steamed veggies, or maybe some Mexican rice work great alongside these filling layers for a simple meal.

Tex-Mex Beef Layers

Dig into layers of spiced beef, chunky salsa, and gooey cheese all topping a flaky biscuit base.

Prep Time
20 min
Cooking Time
40 min
Total Time
60 min
By Monica: Monica

Category: Fusion Main Dishes

Skill Level: Moderate

Cuisine Style: Tex-Mex

Yield: 8 Servings (A full 9 x 13 inch casserole)

Dietary Preferences: ~

What You'll Need

→ Casserole Base

01 Cooking spray
02 1 cup water
03 2 1/2 cups of biscuit mix (Bisquick or similar)

→ Filling and Cheese Topping

04 1.5 pounds of lean ground beef
05 1 yellow onion, diced
06 1 red bell pepper, seeded and chopped up
07 1 ounce packet of taco seasoning
08 1/2 cup mayonnaise
09 1/2 cup sour cream
10 1 teaspoon garlic powder
11 4 ounces diced green chiles, liquids drained
12 1/2 cup mild salsa
13 1 1/2 cups shredded fiesta blend cheddar cheese, split

Step-by-Step Guide

Step 01

Let it cool for about 10 minutes so it’s easier to cut and serve.

Step 02

Slide the dish, uncovered, into the oven for 30 minutes or so. You're done once the top looks bubbly and a beautiful golden color.

Step 03

Spoon drops of salsa on top of the creamy layer. Try not to spread it. Throw on the rest of the cheese so it covers everything.

Step 04

Gently spoon and spread the creamy mix right over the meat mixture. Get as even of a cover as you can.

Step 05

In a bigger bowl, mix the sour cream, mayo, garlic powder, chiles, and about half the cheese. Stir it all until smooth.

Step 06

Dump the beef combo right onto your baked biscuit bottom, and use a spoon to smooth it out to the corners.

Step 07

Toss the onion and bell pepper into the hot beef. Let them cook together a few minutes til soft, add all the taco seasoning, mix, then turn off the heat.

Step 08

Mix your biscuit mix and the water in a bowl until it turns into a dough. Spray your casserole dish with some cooking spray. Press the dough into the dish so it covers the bottom. Give it a quick bake—just until it puffs and barely starts to color—then pull it out.

Step 09

Get a big skillet going on medium-high. Crumble in your ground beef. Stir while it cooks so there's no pink left, then pour off the extra grease.

Step 10

Turn your oven on and set it to 350°F (177°C). Let it get to temperature while you handle the other stuff.

Additional Notes

  1. Want it hotter? Try using spicy salsa or throw some jalapeños into the beef when you’re cooking it.

Essential Tools

  • Big skillet
  • A couple medium bowls
  • 9 x 13 inch baking dish

Allergy Information

Review each ingredient for possible allergens and consult a healthcare professional if you're unsure.
  • You'll find milk and dairy in the cheese, sour cream, and mayo.
  • Contains gluten thanks to biscuit mix.
  • Eggs are in the mayo and possibly in the biscuit mix.

Nutritional Facts (Per Serving)

This info is for reference purposes only and isn't a substitute for medical advice.
  • Calories: 483
  • Fats: 30 g
  • Carbohydrates: 29 g
  • Proteins: 23 g